Notch from Neurodevelopment to Neurodegeneration: Keeping the FateAlain Israel, B. de Strooper, F. Checler, Y. Christen Springer Science & Business Media, 28 мая 2002 г. - Всего страниц: 158 Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development and function require complex cellular and molecular processes controlled by a number of different signaling mechanisms. One such signaling mechanism, the Notch pathway, has been recognized as an important player in the regulation of cellfate decisions during early neural development. However, the action of this evolutionary conserved and widely used cell-cell interaction mechanism is not confined to the developing nervous system. In addition, recent studies have shown that elucidating the mechanism of Notch signaling and its role in the brain is important for our understanding of neurological disorders such as Alzheimer's disease and cerebral arteriopathy CADASIL. |
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Alain Israel, B. de Strooper, F. Checler, Y. Christen. A. Israël B. de Strooper F. Checler Y. Christen ( Eds . ) Notch from Neurodevelopment to Neurodegeneration : Keeping the Fate $ Springer FONDATION IPSEN POUR LA RECHERCHE ...
Alain Israel, B. de Strooper, F. Checler, Y. Christen. A. Israël B. de Strooper F. Checler Y. Christen ( Eds . ) Notch from Neurodevelopment to Neurodegeneration : Keeping the Fate $ Springer FONDATION IPSEN POUR LA RECHERCHE ...
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Alain Israel, B. de Strooper, F. Checler, Y. Christen. A. Israël B. De Strooper F. Checler Y. Christen ( Eds . ) Notch from Neurodevelopment to Neurodegeneration : Keeping the Fate With 50 Figures and 1 Table Springer Israël , Alain , Dr. , ...
Alain Israel, B. de Strooper, F. Checler, Y. Christen. A. Israël B. De Strooper F. Checler Y. Christen ( Eds . ) Notch from Neurodevelopment to Neurodegeneration : Keeping the Fate With 50 Figures and 1 Table Springer Israël , Alain , Dr. , ...
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Alain Israel, B. de Strooper, F. Checler, Y. Christen. Israël , Alain , Dr. , Ph . D. Unité de Biologie Moléculaire de l'Expression Génique URA 1773 CNRS Institut Pasteur 25 rue du Dr Roux 75724 Paris Cedex 15 France De Strooper , Bart ...
Alain Israel, B. de Strooper, F. Checler, Y. Christen. Israël , Alain , Dr. , Ph . D. Unité de Biologie Moléculaire de l'Expression Génique URA 1773 CNRS Institut Pasteur 25 rue du Dr Roux 75724 Paris Cedex 15 France De Strooper , Bart ...
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... Strooper and W. Annaert . 89 BAPP Processing , its Biology and Alzheimer's Disease L. D'Adamio .. 101 Further Analysis of the Nicastrin : Presenilin Complex F. Chen , G. Yu , S. Arawaka , M. Nishimura , T. Kawarai , H. Yu , A. Tandon ...
... Strooper and W. Annaert . 89 BAPP Processing , its Biology and Alzheimer's Disease L. D'Adamio .. 101 Further Analysis of the Nicastrin : Presenilin Complex F. Chen , G. Yu , S. Arawaka , M. Nishimura , T. Kawarai , H. Yu , A. Tandon ...
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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate A. Israel,B. de Strooper,F. Checler,Y. Christen Ограниченный просмотр - 2012 |
Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate Alain Israel,B. de Strooper,F. Checler,Y. Christen Недоступно для просмотра - 2012 |
Часто встречающиеся слова и выражения
Acad Sci USA adherens junction Alzheimer's disease amino acids amyloid precursor protein Annaert antibodies APP and Notch armadillo Artavanis-Tsakonas aspartyl protease Aẞ production assay ATF6 B-catenin BAPP binding Biol Chem brain C-terminal CADASIL cadherin catenin Cell Biol cellular cleaved complex detected differentiation Drosophila elegans encoding endoproteolysis expression F-box fragment function gamma-secretase genes Goldstein JL Greenwald Haass HEK293 cells immunoprecipitated inhibition interaction intramembrane Kopan Levesque ligand mammalian mediates membrane membrane-spanning Mol Cell molecular Mumm mutations N-IC Natl Acad Sci neural neurite neurogenesis neurons Neurosci nicastrin NICD Notch intracellular domain Notch receptors Notch signaling nuclear pathway phenotype phosphorylation presenilin Proc Natl Acad processing proteasome proteolysis proteolytic region regulation residues Rogaeva role Saftig SCAP Schroeter EH Selkoe DJ sequence signal peptide Sisodia SS SREBP ẞAPP St George-Hyslop stably sterols Strooper substrate Thinakaran tion transcription transfected ubiquitin wild-type Wolfe y-secretase activity y-secretase cleavage y-secretase inhibitors y-secretosome Zhang
Популярные отрывки
Стр. 155 - Joutel A, Corpechot C, Ducros A, Vahedi K, Chabriat H, Mouton P, Alamowitch S, Domenga V, Cecillion M, Marechal E, Maciazek J, Vayssiere C, Cruaud C, Cabanis EA, Ruchoux MM, Weissenbach J, Bach JF, Bousser MG, Tournier-Lasserve E (1996) Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia.