Functional Neurobiology of AgingPatrick R. Hof, Charles V. Mobbs Elsevier, 11 янв. 2001 г. - Всего страниц: 960 Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments.
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Стр. vi
... Changes in Cognition 56 A. Language 56 B. Visuospatial Functioning 56 C. Psychomotor Functions 56 D. Executive Functions 57 VIII. Cognitive Changes in Dementia 57 A. De®nition of Dementia 57 B. Cortical versus Subcortical Dementia 57 C ...
... Changes in Cognition 56 A. Language 56 B. Visuospatial Functioning 56 C. Psychomotor Functions 56 D. Executive Functions 57 VIII. Cognitive Changes in Dementia 57 A. De®nition of Dementia 57 B. Cortical versus Subcortical Dementia 57 C ...
Стр. xv
... Changes in GABA 638 D. Age-Related Changes in Antioxidant Enzymes 638 636 637 E. Can Responses of the Central Auditory System Be Modi®ed? 638 F. Summary 639 III. Audiologic Rehabilitation: The Need 639 A. Why Audiological Interventions ...
... Changes in GABA 638 D. Age-Related Changes in Antioxidant Enzymes 638 636 637 E. Can Responses of the Central Auditory System Be Modi®ed? 638 F. Summary 639 III. Audiologic Rehabilitation: The Need 639 A. Why Audiological Interventions ...
Стр. xvii
... Changes to Be Covered 728 II. Morphological Changes 728 A. Cell Number 728 B. Pathological Accumulations 729 C. Connections 729 D. Receptors and Transporters 729 III. Functional Changes 730 A. Presynaptic Changes 730 B. Postsynaptic and ...
... Changes to Be Covered 728 II. Morphological Changes 728 A. Cell Number 728 B. Pathological Accumulations 729 C. Connections 729 D. Receptors and Transporters 729 III. Functional Changes 730 A. Presynaptic Changes 730 B. Postsynaptic and ...
Стр. xviii
... Changes in the Pattern of Gonadotropin Secretion Occur during Middle Age 796 III. Age-Related Changes in GnRH Neurons 797 IV. Age-Related Changes in Afferent Inputs to GnRH Neurons 798 A. The Role of Excitatory and Inhibitory Inputs ...
... Changes in the Pattern of Gonadotropin Secretion Occur during Middle Age 796 III. Age-Related Changes in GnRH Neurons 797 IV. Age-Related Changes in Afferent Inputs to GnRH Neurons 798 A. The Role of Excitatory and Inhibitory Inputs ...
Стр. xix
... Changes in Inputs to the Circadian Clock 870 C. Changes in the Central Pacemaker 871 D. Changes in Function of Effector Systems 873 E. Can Age-Related Changes in Circadian Rhythms Be Attenuated or Reversed? 874 III. Effects of Aging on ...
... Changes in Inputs to the Circadian Clock 870 C. Changes in the Central Pacemaker 871 D. Changes in Function of Effector Systems 873 E. Can Age-Related Changes in Circadian Rhythms Be Attenuated or Reversed? 874 III. Effects of Aging on ...
Содержание
1 | |
51 | |
Senses Sensory Cortices and Primary Afferent Functions | 493 |
Locomotion Basal Ganglia and Muscular Functions | 659 |
Homeostasis Hypothalamus and Related Systems | 737 |
Appendix Basic Genetic Concepts | 941 |
Index | 947 |
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abnormal Acad Acta Neuropathol activity age-related aged monkeys Alzheimer's disease amyloid precursor protein amyotrophic lateral animals antibodies apolipoprotein associated basal forebrain behavioral binding Braak Brain Res cell cerebral cortex changes cholinergic cholinergic basal forebrain cingulate clinical correlation cortical de®cits decrease degeneration Delacourte density deposits disorders elderly entorhinal cortex estrogen factors frontal function gene genetic glucose glutamate receptor Guam hippocampus human identi®ed immunoreactivity in¯uence increased layer lesions Lewy body lobe Mattson memory metabolic Morrison Mufson mutations Natl ndings neocortex neocortical neurites neuro®brillary tangles neuro®lament Neurobiol Neurochem neurodegeneration Neurology neuronal loss Neurosci NMDA receptor nucleus basalis observed Parkinson's disease pathology patients peptide phosphorylation Pick's disease presenilin primate progressive supranuclear palsy re¯ect regions rhesus risk role senile plaques signi®cant signi®cantly spatial speci®c stroke studies subtypes synaptic synuclein task tau proteins temporal tion transgenic mice vascular dementia visual
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Стр. 6 - As many more individuals of each species are born than can possibly survive; and as, consequently, there is a frequently recurring struggle for existence, it follows that any being, if it vary however slightly in any manner profitable to itself, under the complex and sometimes varying conditions of life, will have a better chance of surviving, and thus be naturally selected. From the strong principle of inheritance, any selected variety will tend to propagate its new and modified form.
Стр. 129 - Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird TD, Hardy J, Hutton M, Kukull W, Larson E, LevyLahad E, Viitanen M, Peskind E, Poorkaj P, Schellenberg G, Tanzi R, Wasco W, Lannfelt L, Selkoe D...
Стр. 83 - R. (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment.
Стр. 153 - Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, Petersen RC, Stevens M, de Graaff E, Wauters E, van Baren J, Hillebrand M, Joosse M, Kwon JM, Nowotny P...
Стр. 19 - Polymeropoulos, MH, Lavedan, C., Leroy, E., Ide, SE, Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, ES, Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, WG, Lazzarini, AM, Duvoisin, RC, Di lorio, G., Golbe, LI, and Nussbaum, RL, 1997, Mutation in the alpha-synuclein gene identified in families with Parkinson's disease, Science.
Стр. 75 - Oltvai, ZN, Milliman, CL, and Korsmeyer, SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
Стр. 208 - Frackowiak, RSJ, Lenzi, GL, Jones, T. and Heather, JD (1980). 'Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography: theory, procedure and normal values'.
Стр. 404 - Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease.
Стр. 400 - Chartier-Harlin, MC, Crawford, F., Houlden, H., Warren, A., Hughes, D., Fidani, L., Goate, A., Rossor, M., Roques, P.
Стр. 241 - Positron emission tomography and autoradiography: principles and applications for the brain and heart.