Functional Neurobiology of AgingPatrick R. Hof, Charles V. Mobbs Elsevier, 11 янв. 2001 г. - Всего страниц: 960 Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments.
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Стр. vii
... Disorders 11. Vascular Dementia Gabriel Gold, Constantin Bouras, Jean-Pierre Michel, Patrick R. Hof, and Panteleimon ... Disorders with Lewy Bodies Lawrence Hansen and Eliezer Masliah I. Introduction 173 II. Nosology of Disorders with ...
... Disorders 11. Vascular Dementia Gabriel Gold, Constantin Bouras, Jean-Pierre Michel, Patrick R. Hof, and Panteleimon ... Disorders with Lewy Bodies Lawrence Hansen and Eliezer Masliah I. Introduction 173 II. Nosology of Disorders with ...
Стр. x
... Disorders 319 B. Examples of Hereditary Disorders C. Combination of Tau Isoforms and Phosphorylation: A Better Understanding of the Degenerating Process 322 IV. Abnormal Tau Phosphorylation as a Biochemical Marker 322 A. Kinases ...
... Disorders 319 B. Examples of Hereditary Disorders C. Combination of Tau Isoforms and Phosphorylation: A Better Understanding of the Degenerating Process 322 IV. Abnormal Tau Phosphorylation as a Biochemical Marker 322 A. Kinases ...
Стр. xvi
... Disorders in Elderly Patients 679 A. Essential Tremor 679 B. Vascular Parkinsonism 679 C. Multiple System Atrophy 680 D. Progressive Supranuclear Palsy 680 E. Corticobasal Degeneration 681 F. Normal-Pressure Hydrocephalus 681 G ...
... Disorders in Elderly Patients 679 A. Essential Tremor 679 B. Vascular Parkinsonism 679 C. Multiple System Atrophy 680 D. Progressive Supranuclear Palsy 680 E. Corticobasal Degeneration 681 F. Normal-Pressure Hydrocephalus 681 G ...
Стр. 3
... disorders. Analysis and interpretation of age-speci®c disease rates, however, are relatively underappreciated vantage points from which to view aging. A preliminary note of caution is warranted. Age-speci®c rates deal with populations ...
... disorders. Analysis and interpretation of age-speci®c disease rates, however, are relatively underappreciated vantage points from which to view aging. A preliminary note of caution is warranted. Age-speci®c rates deal with populations ...
Стр. 4
... disorders demonstrate a similar pattern. Age-speci®c mortality rates will rise initially at an exponential rate with increasing age. After some age, age-speci®c mortality rates will increase at a slower rate, plateau, or decline. C ...
... disorders demonstrate a similar pattern. Age-speci®c mortality rates will rise initially at an exponential rate with increasing age. After some age, age-speci®c mortality rates will increase at a slower rate, plateau, or decline. C ...
Содержание
1 | |
51 | |
Senses Sensory Cortices and Primary Afferent Functions | 493 |
Locomotion Basal Ganglia and Muscular Functions | 659 |
Homeostasis Hypothalamus and Related Systems | 737 |
Appendix Basic Genetic Concepts | 941 |
Index | 947 |
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abnormal Acad Acta Neuropathol activity age-related aged monkeys Alzheimer's disease amyloid precursor protein amyotrophic lateral animals antibodies apolipoprotein associated basal forebrain behavioral binding Braak Brain Res cell cerebral cortex changes cholinergic cholinergic basal forebrain cingulate clinical correlation cortical de®cits decrease degeneration Delacourte density deposits disorders elderly entorhinal cortex estrogen factors frontal function gene genetic glucose glutamate receptor Guam hippocampus human identi®ed immunoreactivity in¯uence increased layer lesions Lewy body lobe Mattson memory metabolic Morrison Mufson mutations Natl ndings neocortex neocortical neurites neuro®brillary tangles neuro®lament Neurobiol Neurochem neurodegeneration Neurology neuronal loss Neurosci NMDA receptor nucleus basalis observed Parkinson's disease pathology patients peptide phosphorylation Pick's disease presenilin primate progressive supranuclear palsy re¯ect regions rhesus risk role senile plaques signi®cant signi®cantly spatial speci®c stroke studies subtypes synaptic synuclein task tau proteins temporal tion transgenic mice vascular dementia visual
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