Functional Neurobiology of AgingPatrick R. Hof, Charles V. Mobbs Elsevier, 11 янв. 2001 г. - Всего страниц: 960 Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments.
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Стр. xiv
... Temporal Processing: Human Subjects 565 A. Speech Recognition in the Elderly 565 B. Psychoacoustic Declines in Temporal Gap Detection 567 C. Age-Related Changes in Temporal Processing: Auditory Brain-Stem Response 569 D. Neuroimaging ...
... Temporal Processing: Human Subjects 565 A. Speech Recognition in the Elderly 565 B. Psychoacoustic Declines in Temporal Gap Detection 567 C. Age-Related Changes in Temporal Processing: Auditory Brain-Stem Response 569 D. Neuroimaging ...
Стр. 58
... temporal cortex and hippocampus and found later in the illness in the more lateral structures of the temporal lobe, parietal cortex, and perisylvian region (Khachaturian, 1985; Huff et al., 1987). Plaques are irregularly shaped deposits ...
... temporal cortex and hippocampus and found later in the illness in the more lateral structures of the temporal lobe, parietal cortex, and perisylvian region (Khachaturian, 1985; Huff et al., 1987). Plaques are irregularly shaped deposits ...
Стр. 70
... temporal neocortex, implying that the progression in NFT density within adjacent components of the medial and inferior aspects of the temporal cortex may take place in cognitively intact individuals (Hubbard et al., 1990; Arriagada et ...
... temporal neocortex, implying that the progression in NFT density within adjacent components of the medial and inferior aspects of the temporal cortex may take place in cognitively intact individuals (Hubbard et al., 1990; Arriagada et ...
Стр. 71
... temporal cortex may be a neuropathological hallmark of incipient dementia in elderly patients presenting with normal ... Temporal cortex Silver stains Congo red Thio ̄avin-S Semiquantitative Age-related SP densities SP formation in the ...
... temporal cortex may be a neuropathological hallmark of incipient dementia in elderly patients presenting with normal ... Temporal cortex Silver stains Congo red Thio ̄avin-S Semiquantitative Age-related SP densities SP formation in the ...
Стр. 77
... temporal cortex, especially in layer III of the transentorhinal cortex, in layer II of the entorhinal cortex, and in the hippocampal formaFunctional Neurobiology of Aging tion where the CA1 ®eld and the subiculum display the highest ...
... temporal cortex, especially in layer III of the transentorhinal cortex, in layer II of the entorhinal cortex, and in the hippocampal formaFunctional Neurobiology of Aging tion where the CA1 ®eld and the subiculum display the highest ...
Содержание
1 | |
51 | |
Senses Sensory Cortices and Primary Afferent Functions | 493 |
Locomotion Basal Ganglia and Muscular Functions | 659 |
Homeostasis Hypothalamus and Related Systems | 737 |
Appendix Basic Genetic Concepts | 941 |
Index | 947 |
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abnormal Acad Acta Neuropathol activity age-related aged monkeys Alzheimer's disease amyloid precursor protein amyotrophic lateral animals antibodies apolipoprotein associated basal forebrain behavioral binding Braak Brain Res cell cerebral cortex changes cholinergic cholinergic basal forebrain cingulate clinical correlation cortical de®cits decrease degeneration Delacourte density deposits disorders elderly entorhinal cortex estrogen factors frontal function gene genetic glucose glutamate receptor Guam hippocampus human identi®ed immunoreactivity in¯uence increased layer lesions Lewy body lobe Mattson memory metabolic Morrison Mufson mutations Natl ndings neocortex neocortical neurites neuro®brillary tangles neuro®lament Neurobiol Neurochem neurodegeneration Neurology neuronal loss Neurosci NMDA receptor nucleus basalis observed Parkinson's disease pathology patients peptide phosphorylation Pick's disease presenilin primate progressive supranuclear palsy re¯ect regions rhesus risk role senile plaques signi®cant signi®cantly spatial speci®c stroke studies subtypes synaptic synuclein task tau proteins temporal tion transgenic mice vascular dementia visual
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