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Стр. 817
Abnormally large expanded repeats in RNAs cause DM1 and DM2 . ( Top ) A large expanded CTG repeat in the DMPK gene at the DM1 locus on chromosome 19 causes DM1 . ( Bottom ) A large expanded CCTG repeat in the ZNF9 gene at the DM2 locus ...
Abnormally large expanded repeats in RNAs cause DM1 and DM2 . ( Top ) A large expanded CTG repeat in the DMPK gene at the DM1 locus on chromosome 19 causes DM1 . ( Bottom ) A large expanded CCTG repeat in the ZNF9 gene at the DM2 locus ...
Стр. 864
Myotonic Dystrophy Type 2 Caused by a CCTG Expansion in Intron 1 of ZNF9 4 Christina L. Liquori , 1,2 Kenneth Ricker ... Parallels between these mutations indicate that microsatellite expansions in RNA can be pathogenic and cause the ...
Myotonic Dystrophy Type 2 Caused by a CCTG Expansion in Intron 1 of ZNF9 4 Christina L. Liquori , 1,2 Kenneth Ricker ... Parallels between these mutations indicate that microsatellite expansions in RNA can be pathogenic and cause the ...
Стр. 866
168 174 Our results demonstrate that DM2 is caused by an untranslated CCTG expansion . ... that the CUG and CCUG expansions expressed at the RNA level can themselves be pathogenic and cause the multisystemic features of DM1 and DM2 .
168 174 Our results demonstrate that DM2 is caused by an untranslated CCTG expansion . ... that the CUG and CCUG expansions expressed at the RNA level can themselves be pathogenic and cause the multisystemic features of DM1 and DM2 .
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