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Стр. 1054
H ow do eukaryotic organisms express genes in patterns that are extraordinarily diverse and complex , yet precise in their response to environmental and developmental cues ? Their secret lies in the enhancer , a relatively short region ...
H ow do eukaryotic organisms express genes in patterns that are extraordinarily diverse and complex , yet precise in their response to environmental and developmental cues ? Their secret lies in the enhancer , a relatively short region ...
Стр. 1147
Extracts from such cells contain a nuclease complex , RISC , that specifically degrades mRNAs that are homologous to the dsRNA trigger . The hypothesis that this nuclease constitutes the effector activity of RNAi is strengthened by the ...
Extracts from such cells contain a nuclease complex , RISC , that specifically degrades mRNAs that are homologous to the dsRNA trigger . The hypothesis that this nuclease constitutes the effector activity of RNAi is strengthened by the ...
Стр. 1452
The y - secretase substrates C83 and C99 form stable complexes with PS heterodimers , and mutating one of the key ... However , it seems clear that presenilins do not work alone , that they are part of a larger y - secretase complex .
The y - secretase substrates C83 and C99 form stable complexes with PS heterodimers , and mutating one of the key ... However , it seems clear that presenilins do not work alone , that they are part of a larger y - secretase complex .
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acetylation activity addition addressed analysis animals applications areas assays ASSISTANT associated binding Biol biology Cancer candidate cause cells Center changes chemistry chromosome clinical cloning complex containing curriculum vitae cytoplasm Department discovery disease drug E-mail effect Employer epigenetic Equal et al expected experience expression field function gene genetic genome Health histone human identified imprinted increase indicated individual Institute interactions interest involved laboratory lead letter mechanism Medical Medicine ment methylation molecular mutation Nature observed Opportunity organic Ph.D plants position POSTDOCTORAL potential projects protein record references region regulation responsible RNAi role says School Science scientists sequence Service signal specific structure successful suggest tion transcription University Western blotting