Science, Том 292John Michels (Journalist) American Association for the Advancement of Science, 2001 |
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Стр. 1729
... Akt2 . Western blots of protein ex- tracts prepared from liver , muscle , and iso- lated adipocytes from homozygous knockout ( Akt2- ) mice showed loss of expression of Akt2 ( Fig . 1 ) , without detectable effect on the levels of Akt1 ...
... Akt2 . Western blots of protein ex- tracts prepared from liver , muscle , and iso- lated adipocytes from homozygous knockout ( Akt2- ) mice showed loss of expression of Akt2 ( Fig . 1 ) , without detectable effect on the levels of Akt1 ...
Стр. 1730
... Akt2 - / - ( KO ) mice at 2 to 5 months of age . Data are the mean ± SEM ( P < 0.0001 , Student's t test ) . ( B ) Extensor digitorum longus ( EDL ) or ( C ) soleus muscle was excised from 2- to 3 - month - old WT or Akt2 - / - mice and ...
... Akt2 - / - ( KO ) mice at 2 to 5 months of age . Data are the mean ± SEM ( P < 0.0001 , Student's t test ) . ( B ) Extensor digitorum longus ( EDL ) or ( C ) soleus muscle was excised from 2- to 3 - month - old WT or Akt2 - / - mice and ...
Стр. 1731
... Akt2 is a cell - autonomous result of the kinase deficiency in the muscle cell . Although the simplest interpretation of our findings is that Akt2 represents an obli- gate intermediate in the pathway by which insulin acutely regulates ...
... Akt2 is a cell - autonomous result of the kinase deficiency in the muscle cell . Although the simplest interpretation of our findings is that Akt2 represents an obli- gate intermediate in the pathway by which insulin acutely regulates ...
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