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Стр. 1911
L14Q / F19S L220 / W23S Positive nuclear export Negative nuclear export 3 4 5 6 7 8 CMV - p53 CMV - p53L140 / F195 CMV - p53L220 W238 5 p53L140 / F195 3 3 3 31 U - 205 Fig . 1. p53 nuclear export is impaired by mutations in the NH ...
L14Q / F19S L220 / W23S Positive nuclear export Negative nuclear export 3 4 5 6 7 8 CMV - p53 CMV - p53L140 / F195 CMV - p53L220 W238 5 p53L140 / F195 3 3 3 31 U - 205 Fig . 1. p53 nuclear export is impaired by mutations in the NH ...
Стр. 1912
Twenty hours after transfection , cells were fused with p53 - deficient human Saos - 2 cells that had been infected with adenovirus expressing ARF . p53 nuclear export was examined by heterokaryon assay .
Twenty hours after transfection , cells were fused with p53 - deficient human Saos - 2 cells that had been infected with adenovirus expressing ARF . p53 nuclear export was examined by heterokaryon assay .
Стр. 1914
DNA damage - induced , Ser 15 - phosphorylated p53 is blocked from nuclear export . ( A ) Plasmids expressing various GFP fusions linked with WT or mutant p53 peptide were transfected into U - 20S cells . Forty - eight hours after ...
DNA damage - induced , Ser 15 - phosphorylated p53 is blocked from nuclear export . ( A ) Plasmids expressing various GFP fusions linked with WT or mutant p53 peptide were transfected into U - 20S cells . Forty - eight hours after ...
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acid activation addition agrin analysis applications ASSOCIATE binding biology Cancer candidate cells Center complex computational concentrations containing cytoplasmic Department direction Director disease domain drug E-mail effect electron emission energy Equal et al experience expression factor field function funding gene genetic genome glucose growth Health human imaging increase indicated individual initial Institute interaction interest Laboratory lead MANAGER measured Medical Medicine method mice molecular mutant Nature nuclear observed ocean Opportunity organization Ph.D plants Pleistocene population position present projects protein receptor references region response sample says School Science scientific scientists sequence Service signaling specific splenocytes structure studies suggest tion transcription tubby United Univ University