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" Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. "
Proteases as Targets for Therapy - Стр. 393
редактор(ы): - 2000 - Страниц: 410
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Findings and Current Opinion in Cognitive Neuroscience

Larry R. Squire, Stephen Michael Kosslyn - 1998 - Страниц: 396
...Citron M, 5uzuki N, •• Bird TD, Hardy l, Hutton M, Kukull W et al.: The amyloid B protein deposited in the senile plaques of Alzheimer's disease is increased...mutations linked to familial Alzheimer's disease. Nat Med 1996. 2:864-870, The study shows increased levels of highly amyloidogenic Ap^peptide ending at Afi42i43I...
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Progress in Alzheimer’s and Parkinson’s Diseases

Abraham Fisher, Israel Hanin, Mitsuo Yoshinda - 1998 - Страниц: 916
...0., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D., and Younkin, S., 1996, Secreted amyloid peptide (3-protein similar to that in the senile plaques of...Alzheimer's disease is increased in vivo by the presenilin I and 2 and APP mutations linked to familial Alzheimer's disease, Nature Mcd. 2:864—870. Wallace,...
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Molecular Biology of Alzheimer's Disease: Genes and Mechanisms Involved in ...

Christian Haass - 2003 - Страниц: 350
...Younkin, S. (1996) Secreted Amyloid Beta-Protein Similar to That In the Senile Plaques Of Alzheimers Disease Is Increased In vivo By the Presenilin 1 and 2 and App Mutations Linked to Familial Alzheimers Disease. Nature Medicine, 2, 864-870. Schwartz, L., and Milligan, C. (1996) Cold thoughts...
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Neurogenetics, Выпуск 495

Stefan-M. Pulst - 2000 - Страниц: 496
...Neurosci Abstr 21: 1500, 1995. 101. 84. Scheuner D, Eckman C.Jensen M, et al.: Secreted amyloid В protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo 102. by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 2:...
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Management of Aging: The University of Geneva Experience

Jean-Pierre Michel, Patrick R. Hof - 1999 - Страниц: 277
...P, Schellenberg G, Tanzi R, Wasco W, Lannfelt L, Selkoe DJ, Younkin S: Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's...mutations linked to familial Alzheimer's disease. Nat Med 1996;2:864-870. 29 Grunberg J, Walter J, Loetscher H, Deuschle U, Jacobsen H, Haass C: Alzheimer's...
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Amyloid and Amyloidosis 1998: Proceedings of the VIIIth International ...

R.A. Kyle, M.A. Gertz - 1999 - Страниц: 612
...locus. Science 269, 973-977. 10. Scheuner. D., Eckman, C., et al. (1996). Secreted amyloid p-protein similar to that in the senile plaques of Alzheimer's...mutations linked to familial Alzheimer's disease. Nature Med. 2, 864-870 11. Lemere, CA, Lopera, F., et al. (1996). The E280A presenilin 1 Alzheimer...
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Calpains: Pharmacology and Toxicology of a Cellular Protease

K K W Wang, Po-wai Yuen - 1999 - Страниц: 472
...Eckman. C., Jensen. M., Song. X., Citron. M., Suzuki. N., et al. l996. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased tn vivo by the presenilin l and 2 and APP mutations linked to familial Alzheimer's disease. Nature...
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Towards Evolvable Hardware: The Evolutionary Engineering Approach

Eduardo Sanchez, Marco Tomassini - 1996 - Страниц: 528
...Schellenberg G, Tanzi R, Wasco, W, Lannfelt L, Selkoe D, Younkin S ( 1 996) Secreted amyloid bprotein similar to that in the senile plaques of Alzheimer's...mutations linked to familial Alzheimer's disease. Nat Med 2: 864-870 54. Mattson MP, Barger SW, Cheng B, Lieberburg I, Smith-Swintosky VL, Rydel RE (1993) p-amyloid...
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Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders

M.M. Verbeek, Harry V. Vinters, R.M. de Waal - 2000 - Страниц: 400
...Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, et al (1996) Secreted amyloid p-protein similar to that in the senile plaques of Alzheimer's...linked to familial Alzheimer's disease. Nat. Med. 2, 864-870. 79. Mann DMA, Iwatsubo T, Cairns NJ, Lantos PL, Nochlin D, Sumi SM, et al (1996) Amyloid...
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Membrane Structure in Disease and Drug Therapy

Svante Cornell - 2000 - Страниц: 570
...Poorkaj P. Schellenberg G. Tanzi R. Wasco W. Lannfelt L. Selkoe D. Younkin S. Secreted amyloid p-protein similar to that in the senile plaques of Alzheimer's...mutations linked to familial Alzheimer's disease. Nature Med 1996: 2:864-870. 7. Jarrett JT. Berger EP. Lansbury PT Jr. The carboxy terminus of the p...
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