Synaptic Modifications and Memory: An Electrophysiological AnalysisSpringer Berlin Heidelberg, 27 мая 1993 г. - Всего страниц: 303 Understanding of memory and learning is one of the major goals of neuroscientists and psychologists. The author first introduces the reader into the current state of knowledge of the mechanisms underlying memory by providing extensive reviews of contemporary results including behavioural approaches and molecular studies. He presents results of his group obtained by analysing elec- trical activity - including single neuron meassures. As a major experimental model the phenomenon of hippocampal long- term potentiation was studied. The so-called quantal analy- sis - a quantitative method - was applied to study mammalian brain plasticity. Short- and long-term synaptic plasticities were registered both in vivo and in vitro mammalian brain preparations. Results show the involvement of mainly presynaptic location in memory, however, the possible involvement of postsynaptic mechanisms is indicated by changes in quantal amplitude as shown by the author. |
Результаты поиска по книге
Результаты 1 – 3 из 82
Стр. 41
... similar to that of the responses evoked by weak near - threshold stimulation of area CA3 ( Fig . 3.2A2 ) . 3.5 ... Similar stimulus - response curves with discrete transitions ( plateaux and steps ) were obtained in 10 out of 16 similar ...
... similar to that of the responses evoked by weak near - threshold stimulation of area CA3 ( Fig . 3.2A2 ) . 3.5 ... Similar stimulus - response curves with discrete transitions ( plateaux and steps ) were obtained in 10 out of 16 similar ...
Стр. 75
... similar to that on the septo - hippocampal responses ( compare Fig . 6.4A1 and B1 , columns ) . Changes in ACh sensitivity studied with 24 tetanic stimulations of the medial septum and 7 tetanizations of the DG were also similar to ...
... similar to that on the septo - hippocampal responses ( compare Fig . 6.4A1 and B1 , columns ) . Changes in ACh sensitivity studied with 24 tetanic stimulations of the medial septum and 7 tetanizations of the DG were also similar to ...
Стр. 102
... similar conditions [ 850-852 ] . A decrease in v during long - lasting stimulation without hemicholinium pretreatment was also indicated by recordings from neurones at the goldfish brainstem [ 728 ] but without a special quantal ...
... similar conditions [ 850-852 ] . A decrease in v during long - lasting stimulation without hemicholinium pretreatment was also indicated by recordings from neurones at the goldfish brainstem [ 728 ] but without a special quantal ...
Содержание
LongTerm Potentiation of Field Potentials | 10 |
1 | 16 |
4 | 22 |
Авторские права | |
Не показаны другие разделы: 31
Другие издания - Просмотреть все
Synaptic Modifications and Memory: An Electrophysiological Analysis Leon L. Voronin Ограниченный просмотр - 2012 |
Synaptic Modifications and Memory: An Electrophysiological Analysis L. L. Voronin Просмотр фрагмента - 1993 |
Synaptic Modifications and Memory: An Electrophysiological Analysis L. L. Voronin Просмотр фрагмента - 1993 |
Часто встречающиеся слова и выражения
activity afferent Aplysia area CA1 averaged behavioural binomial distribution binomial model Brain Res Ca2+ calculated cells Chap conditioning correlation deconvolution decrease dentate gyrus depletion model depolarization depression electrodes EPSP amplitude EPSPs recorded estimates excitatory experimental experiments F₁ fibres frequency hippocampal hippocampal EPSPs hippocampal neurones hippocampal slices histogram histogram method hyperpolarization induced inhibitory initial input intracellular recordings iontophoresis IPSP latency long-lasting long-term potentiation low-frequency LPa2 LTP induction LTP magnitude membrane minimal EPSPs minimal FPs monosynaptic motoneurones MPSPs neuromuscular junction Neurosci observed obtained pathway Physiol Lond Poisson population spike post-tetanic changes presynaptic pretetanic PSPs pyramidal layer quantal analysis quantal parameters quantum hypothesis receptors region responses Schaffer collaterals Sect significant similar single small LTP spinal motoneurones statistical studies synaptic plasticity synaptic transmission testing stimuli tetanic stimulation tion transmitter release unitary EPSPs UPSPs values variant vertebrate vitro vivo