Science, Том 311,Выпуски 5763-5769John Michels (Journalist) 2006 |
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Стр. 1142
... NEMO ( also called IKKy ) . An- other important regulatory component of the IKK complex is a protein called ELKS ( 3 ) . Upon activation , IKK phosphorylates IKB to promote its ubiquitin - dependent degradation . Liberated NF - KB then ...
... NEMO ( also called IKKy ) . An- other important regulatory component of the IKK complex is a protein called ELKS ( 3 ) . Upon activation , IKK phosphorylates IKB to promote its ubiquitin - dependent degradation . Liberated NF - KB then ...
Стр. 1143
... NEMO α - NEMO NEMO 1 2 3 4 5 6 α - ΑΤΜ α - ATR L - 40 TNF VP16 AT59 TNF VP16 IR Dox CPT TNFα 1 2 . 3 4 5 6 7 8 9 10 3 - pS85- NEMO E VP16 : + -Мус Lysate IP Ctrl IgG : + 1 2 3 4 5 α - ΑΤΜ : + + VP16 : - + + α - ΑΤΜ C VP16 WB α - ΝΕΜΟ ...
... NEMO α - NEMO NEMO 1 2 3 4 5 6 α - ΑΤΜ α - ATR L - 40 TNF VP16 AT59 TNF VP16 IR Dox CPT TNFα 1 2 . 3 4 5 6 7 8 9 10 3 - pS85- NEMO E VP16 : + -Мус Lysate IP Ctrl IgG : + 1 2 3 4 5 α - ΑΤΜ : + + VP16 : - + + α - ΑΤΜ C VP16 WB α - ΝΕΜΟ ...
Стр. 1144
... NEMO and p65 nuclear staining varied from ~ 20 to 40 % of exposed cells in different experiments , which cor- related with the overall magnitude of NF - кВ- A B NEMO - WT NEMO - S85A NEMO - WT Ub - S85A VP16 : HA - Ub : + + LVC LVC + + ...
... NEMO and p65 nuclear staining varied from ~ 20 to 40 % of exposed cells in different experiments , which cor- related with the overall magnitude of NF - кВ- A B NEMO - WT NEMO - S85A NEMO - WT Ub - S85A VP16 : HA - Ub : + + LVC LVC + + ...
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