foundest of all infidelity-the fear lest the truth be bad. On the other hand, the sincere man of science, content to follow wherever the evidence leads him, becomes by each new inquiry more profoundly convinced that the Universe is an insoluble problem. Alike in the external and the internal worlds, he sees himself in the midst of ceaseless changes, of which he can discover neither beginning nor end. If, tracing back the evolution of things, he allows himself to entertain the hypothesis that all matter once existed in a diffused form, he finds it impossible to conceive how this came to be so; and equally, if he speculates on the future, he can assign no limit to the grand succession of phenomena ever unfolding themselves before him. Similarly, if he looks inward, he perceives that both terminations of the thread of consciousness are beyond his grasp he cannot remember when or how consciousness commenced, and he cannot examine the consciousness at any moment existing; for only a state of consciousness which is already past can become the object of thought, and never one which is passing. When, again, he turns from the succession of phenomena, external or internal, to their essential nature, he is equally at fault. Though he may succeed in resolving all properties of objects into manifestations of force, he is not thereby enabled to conceive what force is; but finds, on the contrary, that the more he thinks about it, the more he is baffled. Similarly, though analysis of mental actions may finally bring him down to sensations as the original materials out of which all thought is woven, he is none the forwarder; for he cannot in the least comprehend sensation. Inward and outward things he thus discovers to be alike inscrutable in their ultimate genesis and nature. He sees that the Materialist and Spiritualist controversy is a mere war of words; the disputants being equally absurd-each believing he understands that which it is impossible for any man to understand. In all directions his investigations even

tually bring him face to face with the unknowable; and he ever more clearly perceives it to be the unknowable. He learns at once the greatness and the littleness of human intellect-its power in dealing with all that comes within the range of experience; its impotence in dealing with all that transcends experience. He feels more vividly than any others can feel, the utter incomprehensibleness of the simplest fact, considered in itself. He alone truly sees that absolute knowledge is impossible. He alone knows that under all things there lies an impenetrable mystery.

UNIVERSITY

OF

CALIFORNIA

TRANSCENDENTAL PHYSIOLOGY.

[First published in The National Review for October, 1857, under the title of "The Ultimate Laws of Physiology". The title Transcendental Physiology", which the editor did not approve, was restored when the essay was re-published with others in 1857.]

THE title Transcendental Anatomy is used to distinguish that division of biological science which treats, not of the structures of individual organisms considered separately, but of the general principles of structure common to vast and varied groups of organisms,-the unity of plan discernible throughout multitudinous species, genera, and orders, which differ widely in appearance. And here, under the head of Transcendental Physiology, we purpose putting together sundry laws of development and function which hold not of particular kinds or classes of organisms, but of all organisms: laws, some of which have not, we believe, been hitherto enunciated.

By way of unobtrusively introducing the general reader to biological truths of this class, let us begin by noticing one or two with which he is familiar. Take first, the relation between the activity of an organ and its growth. This is a universal relation. It holds, not only of a bone, a muscle, a nerve, an organ of sense, a mental faculty; but of every gland, every viscus, every element of the body. It is seen, not in man only, but in each animal which affords us adequate opportunity of tracing it. Always providing that the performance of function is not so excessive as to produce disorder, or to exceed the repairing powers either of the system at large or of the particular agencies by which nutriment is brought to the organ,—always providing

this, it is a law of organized bodies that, other things equal, development varies as function. On this law are based all maxims and methods of right education, intellectual, moral, and physical; and when statesmen are wise enough to see it, this law will be found to underlie all right legislation.

Another truth co-extensive with the organic world, is that of hereditary transmission. It is not, as commonly supposed, that hereditary transmission is exemplified merely in re-appearance of the family peculiarities displayed by immediate or remote progenitors. Nor does the law of hereditary transmission comprehend only such more general facts as that modified plants or animals become the parents of permanent varieties; and that new kinds of potatoes, new breeds of sheep, new races of men, have been thus originated. These are but minor exemplifications of the law. Understood in its entirety, the law is that each plant or animal produces others of like kind with itself: the likeness of kind consisting not so much in the repetition of individual traits as in the assumption of the same general structure. This truth has been made by daily illustration so familiar as nearly to have lost its significance. That wheat produces wheat,-that existing oxen are descended from ancestral oxen, -that every unfolding organism ultimately takes the form of the class, order, genus, and species from which it sprang; is a fact which, by force of repetition, has assumed in our minds the character of a necessity. It is in this, however, that the law of hereditary transmission is principally displayed; the phenomena commonly named as exemplifying it being quite subordinate manifestations. And the law, as thus understood, is universal. Not forgetting the apparent, but only apparent, exceptions presented by the strange class of phenomena known as "alternate generation," the truth that like produces like is common to all types of organisms.

Let us take next a universal physiological law of a less conspicuous kind. To the ordinary observer, it seems that

the multiplication of organisms proceeds in various ways. He sees that the young of the higher animals when born resemble their parents; that birds lay eggs, which they foster and hatch; that fish deposit spawn and leave it. Among plants, he finds that while in some cases new individuals grow from seeds only, in other cases they also grow from tubers; that by certain plants layers are sent out, take root, and develop new individuals; and that many plants can be reproduced from cuttings. Further, in the mould that quickly covers stale food, and the infusoria that soon swarm in water exposed to air and light, he sees a mode of generation which, seeming inexplicable, he is apt to consider "spontaneous." The reader of popular science thinks the modes of reproduction still more various. He learns that whole tribes of creatures multiply by gemmation -by a development from the body of the parent of buds which, after unfolding into the parental form, separate and lead independent lives. Concerning microscopic forms of both animal and vegetal life, he reads that the ordinary mode of multiplication is by spontaneous fission-a splitting up of the original individual into two or more individuals, which by and by severally repeat the process. Still more remarkable are the cases in which, as in the Aphis, an egg gives rise to an imperfect female, from which other imperfect females are born viviparously, grow, and in their turns bear other imperfect females; and so on for eight, ten, or more generations, until finally, perfect males and females are viviparously produced. But now under all these, and many more, modified modes of multiplication, the physiologist finds complete uniformity. The starting-point, not only of every higher animal or plant, but of every clan of organisms which by fission or gemmation have sprung from a single organism, is always a spore, seed, or ovum. The millions of infusoria or of aphides which, by sub-division or gemmation, have proceeded from one individual; the countless plants which have been successively propagated from one original plant