Science, Том 323,Выпуски 5917-5922American Association for the Advancement of Science, 2009 |
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Стр. 1057
... caspase 3 and caspase 1 in bone marrow - derived macrophages . We identified the HIN - 200 family member and candidate lupus Susceptibility factor , p202 , as a dsDNA binding protein that bound stably and rapidly to transfected DNA ...
... caspase 3 and caspase 1 in bone marrow - derived macrophages . We identified the HIN - 200 family member and candidate lupus Susceptibility factor , p202 , as a dsDNA binding protein that bound stably and rapidly to transfected DNA ...
Стр. 1059
... Caspase 3 S6 Caspase 1 Fig . 4. HIN - 200 factors regulate DNA - dependent caspase activation . ( A ) Knockdown of p202 enhances DNA - induced caspase 3 and caspase 1 activation . BALB / c BMMs were electroporated with the indicated ...
... Caspase 3 S6 Caspase 1 Fig . 4. HIN - 200 factors regulate DNA - dependent caspase activation . ( A ) Knockdown of p202 enhances DNA - induced caspase 3 and caspase 1 activation . BALB / c BMMs were electroporated with the indicated ...
Стр. 1060
... caspase 1 caspase was more pronounced with reduced p202 , whereas use of siRNAs against the related protein p204 , as well as TLR9 , had no effect . Thus , p202 is not a DNA receptor mediating caspase activation , but instead ...
... caspase 1 caspase was more pronounced with reduced p202 , whereas use of siRNAs against the related protein p204 , as well as TLR9 , had no effect . Thus , p202 is not a DNA receptor mediating caspase activation , but instead ...
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