Science, Том 317,Выпуски 5841-5846John Michels (Journalist) American Association for the Advancement of Science, 2007 |
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Стр. 1227
... mutations at other residues remains poorly understood . We demonstrate that a single cytosine on the top ( nontemplate ) strand is sufficient to recruit AID and lead to mutations of upstream and downstream A / T residues . In contrast ...
... mutations at other residues remains poorly understood . We demonstrate that a single cytosine on the top ( nontemplate ) strand is sufficient to recruit AID and lead to mutations of upstream and downstream A / T residues . In contrast ...
Стр. 1228
... mutations per base pair . n.d. , not done . 1.5 × 10-4 1.1 x 104 3.0 × 10-5 1.0 × 10-4 2.7 x 10-5 1.1 x 10-4 TgG * Number of different founder lines from which mutation data were collected . † Range of expression of the transgene in the ...
... mutations per base pair . n.d. , not done . 1.5 × 10-4 1.1 x 104 3.0 × 10-5 1.0 × 10-4 2.7 x 10-5 1.1 x 10-4 TgG * Number of different founder lines from which mutation data were collected . † Range of expression of the transgene in the ...
Стр. 1229
... mutations 57 53 53 26 62 60 35 Mutations in A / T stretch / Total index of the region ( P = 0.0064 ) ( Fig . 2 ) . The residual level of A / T tract mutation in TgC was comparable to the level seen in TgG , both in WT ( 6/53 ) and Msh2 ...
... mutations 57 53 53 26 62 60 35 Mutations in A / T stretch / Total index of the region ( P = 0.0064 ) ( Fig . 2 ) . The residual level of A / T tract mutation in TgC was comparable to the level seen in TgG , both in WT ( 6/53 ) and Msh2 ...
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