Special Report to the U.S. Congress on Alcohol & HealthDepartment of Health, Education, and Welfare, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Alcohol Abuse and Alcoholism, 1993 |
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Стр. vi
... rats and alcohol- nonpreferring rats .. 117 3 . Mouse in the elevated plus maze apparatus 119 4 . The conditioned taste aversion procedure used to measure aversion to a drug treatment in rats . 121 CHAPTER 6. PSYCHOLOGICAL , SOCIAL ...
... rats and alcohol- nonpreferring rats .. 117 3 . Mouse in the elevated plus maze apparatus 119 4 . The conditioned taste aversion procedure used to measure aversion to a drug treatment in rats . 121 CHAPTER 6. PSYCHOLOGICAL , SOCIAL ...
Стр. 65
... rats exposed to large amounts of alcohol prior to and at the point of conception have tended toward lower birth weight ( Abel and Lee 1988 ) , increased susceptibility to infec- tion and stress ( Abel et al . 1990 ) , poorer maze ...
... rats exposed to large amounts of alcohol prior to and at the point of conception have tended toward lower birth weight ( Abel and Lee 1988 ) , increased susceptibility to infec- tion and stress ( Abel et al . 1990 ) , poorer maze ...
Стр. 66
... rats ( HAS / LAS ) High - alcohol - drinking / Low - alcohol - drinking rats ( HAD / LAD ) Withdrawal - seizure - prone / Withdrawal - seizure - resistant mice ( WSP / WWSR ) SOURCE : Adapted from Crabbe 1989 . Selection trait factors ...
... rats ( HAS / LAS ) High - alcohol - drinking / Low - alcohol - drinking rats ( HAD / LAD ) Withdrawal - seizure - prone / Withdrawal - seizure - resistant mice ( WSP / WWSR ) SOURCE : Adapted from Crabbe 1989 . Selection trait factors ...
Стр. 67
... rats , with a high preference for alcohol , and the alcohol - nonpreferring ( NP ) line of rats , with a low alcohol preference ( Li et al . 1981 ) . The suc- cessful breeding of P and NP rats provided an ex- perimental model for the ...
... rats , with a high preference for alcohol , and the alcohol - nonpreferring ( NP ) line of rats , with a low alcohol preference ( Li et al . 1981 ) . The suc- cessful breeding of P and NP rats provided an ex- perimental model for the ...
Стр. 68
... rats , Allan et al . ( 1991 ) demon- strated that HAS rats were more sensitive than LAS rats to the potentiating effect of alcohol on GABA , thus suggesting that a genetic correlation exists between initial sensitivity to alcohol and ...
... rats , Allan et al . ( 1991 ) demon- strated that HAS rats were more sensitive than LAS rats to the potentiating effect of alcohol on GABA , thus suggesting that a genetic correlation exists between initial sensitivity to alcohol and ...
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5-HT3 receptor abstinence acetaldehyde activity acute Addict adolescent alco alcohol abuse Alcohol Clin Exp alcohol consumption alcohol dehydrogenase alcohol dependence alcohol disorders alcohol exposure alcohol intake alcohol involvement alcohol problems alcohol use disorders alcohol-induced alcohol-related problems alcoholism treatment animals anxiety anxiolytic assessment associated behavior benzodiazepines Biochem brain capita cells chronic alcohol cirrhosis Clin Exp Res clinical cohol comorbid creased decrease depression diagnosis differences disease dopamine drinkers drinking patterns effects of alcohol ethanol ethnic factors fects females fetal function GABA GABAA receptor gene genetic groups Health heavy drinking Hispanic holism impaired increased individuals injury interventions ion channel isoenzymes levels liver Lumeng males ment metabolism mice neurons neurotransmitter NMDA receptor percent Pharmacol physical dependence population potential prenatal prevalence prevention protein psychiatric disorders Psychol rats reported role sample schizophrenia Schuckit sensitivity serotonin social Stud Alcohol studies substance abuse subunits suggest survey symptoms syndrome tion women
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Стр. 304 - Daily or almost daily 6. How often during the last year have you needed a first drink in the morning to get yourself going after a heavy drinking session? Never Less than monthly Monthly Weekly Daily or almost daily 7. How often during the last year have you had a feeling of guilt or remorse after drinking?
Стр. 272 - According to the Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects.
Стр. 340 - Endicott J, Spitzer RL: A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia.
Стр. 122 - CHIARA, G. AND IMPERATO, A.: Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Стр. 123 - Murad. F., eds. The Pharmacological Basis of Therapeutics . 7th ed. New York: Macmillan Publishing Co..
Стр. 304 - Daily or almost daily 8. How often during the last year have you been unable to remember what happened the night before because you had been drinking?
Стр. 223 - Day, NL; Jasperse, D.; Richardson, G.; Robles, N.; Sambamoorthi, U.; Taylor, P.; Scher, M.; Stoffer, D.; and Cornelius, M.
Стр. 106 - Kelly, K., Cochran, BH, Stiles, CD, and Leder, P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and plateletderived growth factor.
Стр. 105 - Ethanol regulation of adenosine receptorstimulated cAMP levels in a clonal neural cell line: An in vitro model of cellular tolerance to ethanol. Proc Nati Acad Sei USA 83:2105-2108, 1986.
Стр. xx - Alcohol dependence, often called alcoholism, refers to a disease that is characterized by abnormal alcohol-seeking behavior that leads to impaired control over drinking. Although alcoholics and alcohol abusers...